Re: 59/Custom in the neck position?
Yes, I have tried a 59/C in the neck with an A8 59/C in the bridge and they sound wonderful.
As to the most popular neck pickups being scooped, I don't much care for them, but if you think about how scooped a Strat is and how much people love their neck tones, you can see why. As for me, I like all my humbuckers to have nice strong mids to them.