Honestly I'm unsure since I've always just played the 490r/498t standards that are in most LPs. I just know I really dislike how thin-sounding they like. My amp is an Orange dark terror. I usually play a lot of sludge/post-metal type things, and generally prefer my cleans to be as warm as possible and distortion to be punchy by emphasizing low mids.
Reason I'm thinking of this combo is I was looking into the Nazgul-Sentient combo. Nazgul sounds good, but clips I've heard seem to have this high-mid spike that I'm not a fan of. Happy for any recommendations other than Alternative 8 as well, but it's just an interesting-sounding pickup from what I've heard.