My search has lead me to begin considering the Mo' Joe, because when I get a pickup with a nice lead tone, the bottom end tends to be loose.
Think Fred or PAF Pro.
When I get a pickup with a tighter low end, the top end is screechy and harsh.
Think Evolution.
What is odd is that I really like the low end of the Evolution for rhythm.
The Evo 2 was very good...it improved the high end, BUT, the low end did become a bit mushy.
I have tried the Screamin' Demon (too toppy), Evolution (tight, but harsh), Evolution 2 (sweeter, but a bit loose on low end), Tone Zone (incredibly fat, but muddy and un-defined), Fred (pretty cool...but, the low end seemed a bit loose), PAF Pro (similar to Fred), Steve's Special (lack of mids is bothersome, but still a pretty cool sound), D-Sonic (thick, too thick), EMG 81 (tight, but sterile) and 85 (sterile, more loose than the 81) and Bill Lawrence L500XL (pretty darn close to what I am looking for, but maybe just a touch too hot, and still not quite as tight as I would like).
Sigh.