Classic Tune-o matics like the ABR-1 or the Nashville useually have a "thinner" spacing. But on a TOM you can also change the spacing by filing the string slots farther apart.
But you´re correct, most modern Tune-O-Matics DO seem to be wider than the "classics"
IIRC hte Tone Wizard generally doesn´t recommend Trembuckers at all, but the only thing that makes that "decision" is string spacing, trust me. THey do sound VEERY minimally different, but I´ll be willing to bet 98% of the players wouldn´t know the difference, evev less in a blind test