At that point I do not have any specific guitar in mind. I was mainly looking for inspiration and the experience of others what worked and in what context. I can then decide what works for me in a particular application.
And I limited the question to hybrids. That is not as broad as using humbuckers in a HH set up.
But if that is still too broad, I'll have another go:
1) Say I had a HSS guitar with two vintage type single coils and I wanted to play blues, country and classic rock with it, which hybrids would work well if I want to have a similar bite out of them and don't want the humbucker to overpower them?
2) Say I had the same HSS guitar but wanted to use a higher output bridge pickup to play 80s hard rock, which hybrid humbucker and which single coils would keep up with a higher output humbucker?
Humcancelling single coils preferred.