Re: Let's take our pickup advice game up a few notches
Why? Because if he says, "Pickup A has more bottom than Pickup B", then this is ALWAYS the case regardless of rig, player, string gauge, recording gear, etc. With the exception of extremely high gain or other extreme situations, these variables are all but completely eliminated by this comparison technique.
However, I used to have a Mexi Strat with stock pickups. The tone of the bridge pickup, even with low gain, was piercing, yet vocal. Like Rob Halford hitting his high notes on Vengeance, Defenders, or Victim of Changes. Or Bruce Dickinson on Number of the Beast. The neck pickup tone was very glassy and jangly, with a deep bass tone on the low strings and a sharp bite on the high strings.
Until my singer-guitarist played it and made it howl in a deep, mournful tone. I played the same note on the same string on the same fret through the same amp with the same settings, and even used his pick, and I could not get close. I handed it back to him and he did it again immediately, so it wasn't like I heard it then drove for an hour before trying it.
Ergo, while your method works for you, personal experience proves it will not work for me.
IMO if you're going to do sound clips for internet samples, it should be done direct, either through a vst or a preamp/modeling unit rather than a miked amp, simply to eliminate the room/amp/cab/speaker/mic variables. As well, open strings only, since even fretting a chord can introduce a tonal variation. With open strings, you're limiting the variables to pick attack and the guitar itself. It's dull and one-dimensional, but running through Little Wing with flawless Hendrix/SRV technique might give someone the impression they'll get that tone without the technique.
Open strings would give a better reference point, since you can compare those against your own personal results directly in either a spectrum analyzer function of a daw or piped through an amp/cab. From there, you could determine whether you might need a brighter pickup or darker pickup to recreate the tone of the clip with your guitar and your pick attack.