Re: NPD. Got a Vox today.
I have a couple of the Valvetronix modelers, including the SE. These are flexible units and dish up a lot of versatile tones. I use them for headphone practice and rehearsals, but have not spent a lot of time making presets for any of them. I tend to dial these in on-the-fly, which they handle pretty well.
One thing I will say about these is that when you are going DI you should plan ahead for the headroom wars. I often find the pedal sounds great by itself, but easily gets lost in the mix once the whole band starts playing. I have learned to plan for a little extra clarity in the stand-alone tones in order to compensate for this. I find it best to use the effects sparingly, as these can really turn to mud if you're not careful with them.
That said, the amp and cabinet modeling is great on these units. So good that it tricks me into expecting the "amp" to react more with the guitar when I'm playing. But of course, you won't get that same reactance going DI that you would when standing 3 feet in front of a tube combo, so that's something else to plan for.
I start with amp and cab selection, switch in the desired effects, then tweak the EQ to get a good stand-alone tone. Then I go through and turn everything back a hair to stay out of the mud.
There are several sites out there for exchanging Tonelab patches. You might be able to find some good stuff already built up for you to use as inspiration for your own patches.
http://www.voxamps.com/toneroom/
Hope you're having a happy NPD!