oh man. i have a nitefly m that has seen a whole bunch of pickup swaps. it's a very difficult guitar to get right with pickups, imho. it's pretty dark, but has a very zingy top end to it, probably due to the ss frets and the carbon fiber wrap on the neck.
i pulled the stocks thinking that i would find a suitable replacement from dimarzio. i tried:
air norton bridge / 36th anniversary PAF neck - cool set. output was not what i wanted, and the air norton, while sounding cool in the bridge, didn't have near enough cut for more aggressive styles.
crunch lab / liquifire - also a cool set, but this is the wrong guitar for it. too dark. i would be that alder or basswood would be fantastic for these pups, but the nitefly was the wrong piece of wood.
DActivator set - this is a winner. awesome. high output but great tone. the neck pickup is sweet. they split very well, and work well with the volume and tone knobs for an awesome variety of tone. they sound awesome clean, and killer for higher gain.
you may have to make some alterations to the pickup routes, because they are deep pickups.