Re: Reversed slug/screw humbucker position changes tone?
Slightly rounder tone. A bit less biting.
No. Slugs toward the bridge, assuming all relative distances (poles-to-strings) remain the same as in the original orientation, will result in less roundness and more bite...if you hear a change at all.
Without delving into alloys and pole piece lengths, the most significant reason for this comes down to 2 facts:
1) Slugs, due to their increased mass, produce a greater signal response compared to using screws in the same coil.
2) Placing slugs toward the bridge, which effectively moves the signal-dominant coil farther away from the fundamental harmonic node at the string's half-way point, will result in greater amplification of a very slightly thinner sounding (think: more off-fundamental harmonics/less vibrational energy) area of the string.
Of course, the reality is that the change is so subtle on a balanced-coil pickup that most people won't notice any real-world difference. Further adjustment (ex: bringing the screw coil closer to the strings) can easily offset the change.
Swapping orientation definitely makes more of a difference when using mis-matched coils as seen with many DiMarzios and Duncan's own 59/Custom hybrid.