I've got a parallel/series switch on both of my strat-style guitars - one is H/S/S and the other is all single coils. IMHO putting middle & bridge single coils in series sounds a lot like a bridge humbucker in terms of output - especially bass. The greater distance between the coils changes the sound, but I like it personally. I love having the bridge & neck single coils in series - kind of like a supercharged Tele
It will only be humcancelling when you combine two opposite single coils (one has to be RW/RP).
I've seen drawings for a series/parallel setup using a standard Strat switch, but it doesn't look like the best solution. If you want to keep 2 tone controls, you almost have to use a 4-pole/5-way super switch.
Chip