Re: vertical 2x12 or ported 1x12 or...
There is absolutely NOTHING wrong with a ported cabinet...if it is done right. Thiele was an Australian engineer who in coordination with another Australian engineer named Small created formulas for designing loudspeaker systems. Using the data parameters of the woofer, their calculations could determine the best volume of the box, and by using a port of the proper dimensions, increase the range of the bass response and increase efficiency.
One of my favorite combinations is to use my Mesa Mark Series combos with a Mesa 112 Thiele extension cab with the EVM speaker. It adds tremendous low end punch and projection.
I think what you need to do is correctly assess your needs. In smaller clubs with a tight stage, a smaller open-back cab or combo might be preferable to a closed back cab, as the sound disperses better, and long-throw projection may not be needed. Back in the day, high-volume arena concerts required volume and projection of "full stacks", but modern PAs and mincing techniques have made these monsters nearly obsolete. Of course, there is the "glam" factor.
My favorite cabs, other than the 112 EVM Thiele, are my vertical Mesa 212 and 412 Half-Back cabs. The tops are open, with a slanted baffle, and the bottom is closed. The 212 cab has a ported bottom. This cab is the same as using my combo plus 112. Great for not only a small club, but for bigger stages and venues as well. I've never had a problem hanging with bigger half and full stacks. And one great advantage of this system is that the designer can select a speaker that works well in an open back cab, and a different speaker to maximize the low end from the closed and ported bottom.
So the real question isn't which is best; it's which cab is best suited for your style of music and the venues you'll be using it in. You may eventually find that you need a few different cabs if you play venues both big and small.
Good luck.
Bill