Not really. The 'Zen Master' is a nice lower-gain drive which I have used a ton over the past couple years, but it has few qualities of a Zen Drive into an amp and will not provide you with any real-life reference. The ZDs most unique feature is the voice control which is supposed to be emulated by using the low-cut on the Fractal (likely because the voice control ..is.. a low-cut).
Still, the default clipping diode on Fractal is 'variable' not op-amp (with 12 other choices selectable, op-amp included) + clip 'shape' + some combination of low-cut, hi cut, bass, mid (para), treble, drive, tone, bias, slew etc.. Even if you don't use all of the settings and you choose op-amp the actual drive function/feel and response is not like the ZD in the least IMO. It's missing the super smooth mids. Zen Master is a great drive on it's own though.
However, to geek a bit further if you do want the sound of say the Zen Drive through a Twin (which is phenomenal) skip the drive block and choose the ODS 100 Ford-1 amp. Input drive at 5 straight up and Overdrive set between 4 and 7...and the rest to taste. Done some amazing pre-session trial tracks with that setting and is spot on of using a ZD and Twin which used to be a live rig of mine. RG