Re: 4x12 different speaker combinations
It would sound a tad different because: when you place two speakers together like in a 2- 12, the frequencies they have in common combine & magnify. Ex: if both speakers at a low volume have defined upper mids, those will pop out, but one speaker with unique bass will have that at a low volume while the other might have searing top-end...WHICH I think sounds awesome- alive, chaotic, interesting. So in your case, it will make each speaker more interesting. But when there's 2 speakers, mounted on the same plane, facing the same direction,- the more they match, the more those frequencies jump right out. So the matched speakers will appear louder.
One experiment i tried: I set 2 different 5w amps next to each other, each at a whisper (as in "could you not whisper? I'm trying to hear myself play guitar!"): When both are on, It is actually surprising how RAWKIN' loud (as in,"TURN THAT DOWN before someone calls the cops!")!!! it gets , MORESO when you start to eq them alike.