That tone is the definitive tone of an alder bodied strat, rosewood fretboard, and the neck pickup has to be an Alnico 5, 6.3K. That means you want a very edgy clean tone, a good overdrive, and an alder strat with a set of Surfers, Fralins, Lollars, Chubtones, Fender Fat 50's etc.
For that SRV/Mayer/KWS sound, it's the alder/rosewood/6.3K A5 neck pickup that gets it. And of course, a cranked tube amp and any string gauge 10 or higher.