I'm no luddite by any stretch of the imagination. I dig bells and whistles more than the next guy. I'm a hardware junkie.
That said, it'll be a long time before I'd drop more than Cube 30 money (~$200) on a digital amp.
- I had a lot of problems back when I owned a Line 6. It got sent back to the factory before I concluded that there was something nutty in my basement that caused it to malfunction (the wah wouldn't work when the pedalboard cable was on the concrete floor).
- I know more than one person whose Valvetronix spontaneously died.
- A lot of my gigging friends have had trouble getting their DMAs to "cut" in a live situation.
- Check resale on DMAs. Like the PC you're reading this on, digital amps depreciate a lot faster than tube gear.
DMAs are cool for practice purposes (provided yours doesn't have the gremlins that mine did) but I'd be reluctant to take to a rehearsal or (gasp) a gig as anything more than a backup.
Another thing to keep in mind is power conditioning. Tubes are a lot more tolerant of power surges and voltage fluctuations than SS, especially the circuits in DMAs.
Finally is serviceability. If something goes wrong in a DMA, you're SOL 'til you can get it to a shop. Though shizzle is more likely to happen in a tube amp than a DMA, chances are it's either a tube or a fuse--either of which is easily replaceable at a gig. That's a far cry from the month I was without my Line 6 as it was sent back to the factory.
IMHO, FWIW, YMMV, etc.