I have guitars right now with SuperD's and a TZ. I use/have used them in Strats and Les Paul/Les Paul styles. I really like both.
Hotness: The SuperD is hotter, but not a ton. Both are "hot" pickups
Clarity: The TZ is more clear/articulate, but not a ton.
Thickness: The SuperD is thicker sounding, but not a ton. Both are kind of dense tone.
Compression: The SuperD is a little more compressed, but not a ton. Both are compressed.
Responsiveness: The TZ is a little more responsive to "finger English" or dynamics than the SuperD. The SuperD is that kind of so--hot-it-is-fast/sensitive to respond.
The Tone Zone to me, is like a, but a "little" more of everything. Little more bass, little more mids, little more highs, little more clarity. Maybe a more progressive or refined SuperD. The SuperD is just "that sound" however. When you need that thick, compressed, 70's hard rock tone, you need the SuperD. When you want to play a little more modern sound, the TZ is the way to go.
Currently: SuperD's in two Les Pauls in the bridge, TZ in an Ibanez RG