Re: Does 59/Custom Hybrid work well in B-standard tuning?
Interesting to read your different results on your journey for the perfect tone. Ive been recommended the Black Winters several times, but I gotta admit Im a little afraid of them.

From the description on seymour duncan they are perfect for anything from hard rock to the blackest black metal, and very clean sounding, however im more into the spectrum Hendrixy psychedelic rock, up to harmonic thrashy metal.
I was a little concerned with the BWs before they arrived too. They are miles ahead of the DiMarzio DActivators that the guitar came with. In fact, it's safe to say I seriously hated the DActivators. When you say harmonics, do you mean a good dollop of midrange? The BWs do have a good amount of midrange which I really like. If I could find something between the Invader and the BW for my bridge, I would be a happy laddy.
I currently have the Duncan distortion, which is amazing for heavy riffs, but too honky and hot for clean.
I have never liked the Duncan Distortion 6 stringer. I can't put my finger on why, it's just always sounded too mean for me, if that makes sense. Which it doesn't since I play metal... I can't think why, it just sounds a bit sterile. I prefer the Dimarzio Super Distortion.
I generally love single coils for alot of stuff, except when Im riffing, so I split my humbuckers with push-pull. I also like a bright sound, so I thought maybe the Alnico 5 magnets in the Hybrid will brighten up my guitars warm alder body.
I wouldn't have said alder was a warm sounding tonewood compared to say mahogany. But then definitions of "warm" etc. aside, if the guitar is quite low-endy sounding, maybe the black winter would do you well given the natural spark in the mid and high-end of the pickup. I think even SD rate it as having a higher midrage and treble than low end.
Heres what I was thinking though; Hybrid pups in bridge ----> Engl powerball II. Since hybrid has alnico 5 magnets it should be fairly responsive and tight for heavy riffing - at the same time its medium output, so it will sound nicer when clean, yet I can get all the distortion I need from my amp.
I'm back and forth on this one almost constantly. To me, high output usually means compressed. Low output means things like pinch harmonics and fluid solo runs or sweeps are a little more difficult to get out. OK sure, it's easy to say work on your technique, but frankly, I find that sort of thing much easier on something like a Dimarzio Super D or Duncan Custom than a Pearly Gates for example.
I really can't comment on the custom/59 hybrid as I have never owned it. But with pickups, guitars and amps, there's plenty of ways to skin that cat! It's a little annoying as "just try it" is a lot of effort. Hopefully my experiences will help you out as from a player's perspective we sound pretty similar. I'm a cross between Hendrix and early Skid Row when it comes to my soloing ability/taste and pretty much straight up 90s groove metal for rhythm tones.
I use the Custom and JB Antiquity in my standard tuned 6 strings, but for detuned 6 strings I rely pretty much entirely on EMG's offerings. They just work really well for all of that.
For my 7 string, while my quest isn't completely over, I'm happy with the BWs. Though I do sometimes swap in the Invader 7 string as well as I just cannot decide which I like more.