IME having a neck anything vs bridge-only is different. Surprisingly, I found that I could get neck tones by changing my hand position. If you are good at adapting your playing, you might not even miss having a neck pickup.
Single-pickup guitars really are different; they force us to get the most out of the one option.
I feel every player should become familiar with at least one at some point in their career.
I could do it with just a neck pickup, but if it was just a bridge pickup, I wouldn't play guitar.
It is not really an issue with humbuckers, since the magnet is under the coils. With single coils it can be an issue, but there aren't many single pickup single coil guitars. Come to think of it, there aren't many double single coil pickup guitars.
Agreed 100%, but I think we are a rare breed...