Aceman finds the best stuff and always makes very insightful observations. Certainly one of the most helpful forum members. Thank you.
IMO, the types of tone dialed in from the amp used can determine the pickup.
I play more with a tone the guy in the first video had. The 498t is my go to pickup for playing rhythm and lead from the same guitar, and I'm a ceramic in the bridge/Alnico II in neck vs. Alnico V guy usually. The 498t is just very balanced. To my ear the 500t is pushing it with that level of gain, and by the time you get to the Dirty Fingers it's like gain, treble, and presence go to 11 and it becomes a fizzy mess.
I think it was a Peavey Triple X amp that had a knob called "hair," which I think was presence, and that's what I think of with these higher output pickups these days--a fizzy, nasally, scratchy mess.
That isn't to say Invaders, Dirty Fingers, X2N, etc., are bad. For the mildly distorted tones the guy in the Tom Delonge video was using, I find the higher output pickups helped out the sound immensely.
So if you're going pop punk, maybe go with the higher output pickups for the way they break up cleans into distortion.
But here is where
alex1fly makes a good point--in the modern world of infinite gain and impulse responses, the high output pickups seem to hurt tone more than they help.
Then again, there's always an exception. From 1987-1998 Chuck Schuldiner used a BC Rich Stealth with a DiMarzio X2N through a boosted Marshall Valvestate. He ended up creating some of the most influential tones in melodic death metal, especially from Human (1991) on. For people of my age and musical tastes, those were some incredible tones obtained from some very modest gear.
But I would say Chuck is an exception. So:
High output pickup = modest amp distortion
Low to mid output pickup = more amp distortion
Also, if I recall James Hetfield briefly used a Dirty Fingers around the Ride the Lightning/Master of Puppets era. Once the ESP/EMG endorsements came in 1987-88, the revolving door of gear stopped for them, but if you like early Metallica tones it may have been a Dirty Fingers out of a Vantage Gibson V copy.
Here is more on that:
https://www.groundguitar.com/james-hetfield-guitars-and-gear/