With the rails design of the dome butter, having two rails pick ups might go well with that. For a true single coil, you could go to vintage rails in the middle, and a cool rails at the neck. That is what I would do.
Or two cool rails in the neck and middle.
I do think that the dimebucker is going to be really bright sounding, and hot rails will be darker sounding in the neck. My intuition tells me that you would have a hard time finding a good EQ on your amplification that would work with both of those pick ups in those positions.
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