I wouldn't worry too much about it. What pedal in particular are you concerned might cause undesirable results?
Many of the usual suspect overdrives don't really "boost" the signal all that much, if any. A relatively hot pickup easily puts out higher peaks than the Tube Screamer ever can at 9V, for example. A Tube Screamer only "appears" louder (if it does at all) because it's a whole lot more compressed. So a really hot pickup technically "hits the input stage" harder than a Tube Screamer does most of the time. Most overdrive pedals are like that including the Bluesbreaker, the Blues Driver, the SD-1, etc. So if a hot pickup is fine on your amp, then so will most stompboxes.
A Klon does have A TON of output by comparison, though.