Re: Mustang Guys
IMO, they do not.
The Stratocaster fulcrum vibrato is a piece of minimalist engineering. The Mustang system is a cheapened version of the "Floating Tremolo" vibrato system of the Jazzmaster and Jaguar.
The feel is different. On the Mustang, the tailpieces shifts but the strings remain at the same height above the pickups and fingerboard. On a Stratocaster, depressing the arm raises the baseplate, shifting the strings away from the pickups and, hence, reducing the output signal strength. (In this respect, the Strat vibrato really does introduce an element of tremolo as a by-product.)
If you keep using both systems, you will adapt to both. If you play the Strat more than the Mustang, the latter will start to feel strange.