So, XSSIVE pretty much nailed it? His may be closer to 10 deg, but still, right in the ballpark. Or close to a EVH Wolfgang if you closed the top horn like the EBMM Axis?
I think the Tele has an advantage in that it has a lot of body to offset, the Strat doesn't have as much to work with, but I believe those Fender high performance strats from the 80s were offset slightly like you are thinking
The Sergio Vallin Fender is almost kind of an offset Strat shape. Fender did release an offset Strat, I believe under the Squier brand, but I can't seem to remember it exactly.
Notice the wonky bridge plate under the synchronized tremolo and the exuberant carving on the treble side cutaway.
Toronado body with Tele layout will do it for me.
Something like this, with better pickguard shape.
If only Fender released it instead of Offset Telecaster with Jazzmaster body.