A lot of the contemporary doom bands go with high wattage "vintage" style amps.
I see them using old Laney heads, Orange heads, Electric amps. Some even use bass heads with guitar cabs.
Some guys use stomp boxes, some use high output pickups.
I've read Matt Pike used Duncan Distortions back in the day. I think Dopesmoker was recorded with Electric amps or Green amps, both of which I think had KT-88's, which is a EL34 style tube, which translates to grainy, warm overdrive.
As far as pickups go, I think Lace has the market cornered on doom/stoner bands.
Needless to say, your tone is your own, so I guess any pickup would do.
Honestly, I got a good doom tone from my 6505 on the clean channel, pre-amp maxed out with high output pickups, no stomp boxes.
I do own a Dirty Hesher bridge, and I have to say, If you're going to hammer you speaker with volume, be ready for the fuzz; the Heshers take care of that.