I play lead and have such pedals as a Fulltone OCD, Way Huge Pork Loin, Pro Co Rat, and use a VOX AC30C2. I like a thick tone for rhythm (I seemed to get this on the Tele) but that keeps that sound where you can clearly hear all the notes ring well.
Save yourself some money and change all the pots to 500KA, instead of changing the pickups.
Next instead of soldering the wire coming from each tone pot to the input leg of each volume pot, try soldering it to the (Middle) output leg of the volume pot. (e.g., 50’s style)
If you still want to change pickups, Antiquity for a classic tone and Joe Bonamassa for a nicer, sweet, and clean hotrod (e.g., hot 59 lester) tone