I've hot the duncan hot rails neck in my HS strat with a black winter bridge. In terms of output it definitely keeps up and sounds muy bueno with the 500ks, it does shine under the higher gain settings, the "sterile" clean sound I keep reading about is to my ears is like an HB with the tone rolled halfway off, with the tone dimed on the rail and gets muddier as you taper down. It retains an all around "warmness" to the sound and sounds good for 80s metal type liquid soloing, and it fuzzez up a bit on the bass, can be good or bad. For my uses (heavy, funky, bluesy rock and hard rock) it pretty much lives in the high gain chorus solo situations. It performs admirably in most higher to high gain settings, I personally will be swapping for a full size HB (thinking sentient), but mine is routed for a neck HB.