Re: PRS S2 series - that much better than an SE?
I think that if I were in the middle of nowhere needing a guitar, a USA PRS is one of the very few brands I feel I could order online and have delivered to my doorstep, and be assured that I'd be getting a great playing guitar.
That said, I will admit that my drug of choice is Gibson, and I don't own any PRS guitars at the moment. The PRS I AM lusting for is one of the original Miras, which might fill my desire for a double-cut LP Special and an SG in one fell swoop. (My fave SG is the '61 Reissue, with the Slim Taper neck, btw. Great guitars!) I have not played many of the S2 models, but it seems to me that the original Mira is a bit better and nicer than the S2 version. The SE guitars are nice for the money, but I think I would rather have a USA-made guitar. I think the design of the Vela is very attractive, and I hope I can try one soon.
If you're not crazy about Gibson, and have some misgivings about the PRS line, I might look elsewhere. The Leo Fender designed ASAT Deluxe is a 2HB, 25.5" bolt neck beauty. Gorgeous finishes on these maple-over-mahogany guitars and a lot of neck options to choose from. If your not set on 2HB, there are several other pickup configurations in the ASAT line. The USA G&Ls are top quality, and definitely a guitar that I would buy off the net, sight unseen or even used--and if buying used they can be great bargains. I have a bunch of G&Ls, most based on the strat body style, and a G&L Legacy is my Number One. So, if your not limited to just PRS, there are other options out there.
Good luck!
Bill