i played on stage with two bands last night using the same guitar and backline fender blues deluxe amp, straight in. guitar is a washburn wms with a seth set, think sg. i used the middle position for 50-60% of the time, just adjusting volumes and tones to taste. amp was set so it was blues rock distorted when the guitar volume was full up, but cleaned up plenty when the volumes were rolled back down. theres magic in that type of setup. at times, one volume would be on 1 and one would be on 3 to get a spanky clean sound, but just having a bit of both pups gives it a different flavor than one pup by itself