I know this is an old topic. I have the everything axe setup with JB Jr bridge, Duckbucker middle and Lil 59 neck along with the coil split toggle switch. I prefer positions 2 and 4 with split coil but sometimes get RF interference from lighting and/or dimmers around the stage. At least that's what I suspect since it doesn't seem like a ground loop hum. The obvious test is to run in dual coil mode and see what happens. Longer term is look at operating some gear off of separate outlets, or trying to relocate myself on stage to see if that helps.
https://www.sweetwater.com/store/de...duncan-everything-axe-strat-pickup-set-white?
https://www.sweetwater.com/store/de...duncan-everything-axe-strat-pickup-set-white?