Re: Speakers wired in series Vs in parallel
If you have a tube power amp, there will be a difference if the resulting impedance is different.
Unlike solid state power transistors which produce the same EQ independently of load (but of course low load causes more power and hence more heat), the power tubes act differently depending on the balance they are in. Different impedance of the speaker cabinets cause different load on the end state transformer and that changes the balance the power tubes are in, which react not only with power but also with sound changes.
There will be no difference in what the amp puts out for similar impedance, e.g. 2x 16 Ohm parallel versus 2x 4 Ohm in series. Of course the different Ohm speaker models might sound different.