Dean Deleo is a strange dude when it comes to guitars. He is really a Tele/single coil guy, and he uses Vox amps primarily. However, on tour is is regularly seen with a Gibson Les Paul.
I recorded a version of Plush, and of Interstate Love Song. I used my Dean Hardtail, which is a PRS type guitar, with the JB in the bridge. It captured the vibe pretty well. The amp was my Boss GT-6, and I used the 1959 Marshall patch, with the gain up pretty good, expecially on Plush, and the mids really boosted to fatten it up. Just a touch of chorus and delay on Plush also, to give it that slightly wierd sound.
Check em out by clicking on my soundclips down in my sig. Nevermind, here's the link.
Jeff's Tunes