I'm fairly certain I'm just not going to be able to have my rig dialed in for the Strat/Tele and the LP as its currently setup. The Fenders are perfect, neck tone is deep and slightly dark, the mid and notch are balanced and the bridge is bright without being harsh.
The LP is just muddy through this setup, but its got huge (older) strings, tuned to C and has a Custom/59 setup. I bet changing back to A2, .010s and E standard will fix these issues. I'll start with the string gauge and tuning. (Either that or reserve the LP for the heavy/metal rig)