Why?
Why?
Just out of curiousity, why do you want to do this?
I don't buy into the line that says that a set neck guitar sustains better than a bolt-on. As for tone, it'll likely sound different but not necessarily "better". Finally, one of the really cool things about a lot of Strat-style guitars is that you can easily replace the neck: unscrew the old one, drill pilot holes in the new one and screw it on. With a set-neck guitar, it's so hard to remove the old neck that a broken neck is the only thing that might make it worth the effort.
IMHO, FWIW, YMMV.