I just experienced over the weekend after being a guitar tech on a small stage how ruined a tone can get by using pedals as the main distortion sound. A guitar tech over the weekend (not me) was managing the main stage of this event which had 2 stacks of mesa triple rectifiers, for both guitarists. Trying to make life easier he decided he'd remove the footswitches (channel switches) and just use pedals to avoid confusing guitarists in between setting up for each band.I notcied how crap the tone was, there was no meat or chunk in the overdrive sound, no dynamics just a fizzy buzzy mess. If only they'd just used the amps distortion they would have killer tone, but no...
I suppose using distortion pedals at home for practice is fine at low volumes ( i use a marshall guvnor) which sounds really nice for marshall type sounds but i never use it live because it takes away alot of my amps tone and gets worse at louder volumes. I like boosters that enhance the sound of your amps exisiting tone or add a little drive.
Its like replacing 2 sets of el34's for a small box with some transitors in it.
My 2 cents, dills