2 Thoughts...
1: I buy a cabinet almost exclusively for the cabinet itself. I can't think of the last time I used stock speakers, even ones that people seem to like (V30s/G12T-75s/etc.) except for certain, high-end Fender combos. The cabinet is both the mechanism of supporting the speakers and the way to reinforce the sonic qualities I'm seeking. Ignoring the ones I've built myself, I tend to have the best luck with Marshalls for classic/hard rock & metal. But I admit this is extremely subjective. (In fact, I did one mid-quality 4x12 for a friend...an MX series slant, and it turned out pretty nicely. Not amazing, but not at all bad. I was surprised at the value in that line. I also have an MX112, but that's for certain utility stuff, as it's very durable, somewhat light, and inexpensive enough that I wouldn't be upset if it takes lumps...sounds alright once the speaker gets changed.)
2: I do as much sound work as I am a musician. I'm not saying that this applies to anyone here, but guitarists that emphasize "lows" are sometimes unaware that, unless their composition is complimentary or interwoven with instruments we expect to be in the basement (bass, kick, etc.), it's very common in my experience for a guitarist on stage or in a recording to be trampling the bass and leaving the upper registers vacant. I try to intercept this when I can, but sometimes people need to hear it go bad first. The electric guitar is an interesting animal. An oboe has a frequency range that's pretty static. Since our instruments are interpreted through circuits, it's possible for us to expand the "normal" range of the guitar beyond it's typical expectations. This is fine and great if everyone is on board and we do it on purpose, but it can also make a band sound...let's say sonically confused...if the guitar periodically drops down and competes with the bass, etc. I like to remind some players, if you really are developing your ears, you can go back to those classic songs you love, and you'll probably find that those guitar tracks were mixed with a much higher bottom end than you remember. I love to crank the bass EQ when I'm practicing or just screwing around on my own, because the fuller sound is nice, but I've also learned to switch that off (on the amp and in my head) when I'm writing, practicing, or on the board. Just something to think about, I guess. No criticism intended.