Re: chambered body vs. guitars with f-holes
I agree. I always thought the 335 was an in-between that didn't really satisfy me from either end. I either want a fully hollow jazzbox with a floating bridge, or a semi-hollow guitar built in the "hollowed solidbody" method.
If the question is about what an f hole does in two exact same guitars, (like Lucille) then the hole will allow air to escape, and that's good or bad depending on what you want. If it suppresses feedback for your rig/volume levels, then don't have an f hole. If you can use one, then the guitar's chamber usually benefits from one. One exception (and it's an exception to many other rules) is the Ibanez Maxxas. That's a closed-chamber clam-shell build, with a dense little trem and a deep-set all access bolt neck, and it's incredibly lively, snappy, vibrant, and responsive. Moreso than most thinline teles or dual cutaways with chambers.
If the question is rather about the construction methods, then there are great differences. Like some solidbody style chambereds have a certain kind of bridge, or bolt neck, or whatever, and that's making a huge difference in the total experience vs. a 335 for example. The f-hole is only a minute part of that equation. You might be comparing a string-through tele bridge with a Gibson tune-o-matic that's mounted on a partially hollowed center block. So there's more at play than just the top/sides/back vs. top/chambered back construction method.