A PLEK machine is a German fretwork automaton that levels your frets after measuring with the strings on, to a very high degree of precision. People seem to be very satisfied with it.
The neck profile of Gilmour's actual Strat is that of a 1983 '57 reissue, which is an incorrect attempt at a 50ties V neck. The 83 reissues have mostly a V neck, but the very back is flat. The whole thing looks a bit like a trapezoid. I had already figured that this probably is the perfect neck shape for me long ago. Unfortunately actual 83 57 reissue Strats cost thousands of $$$, too, now that the hype is on.
Of course, everything we said so far is bull. You see, what the guitar really stands and falls with is the wood that the body is made of, and to a lesser degree the neck.
If you want an actually great Strat there is no other way than going through a lot of bodies and picking the best one. It's not that Gilmour did anything else either.