Yeah, but it depends what kinda vibe you're going for. If you're going for a set that's balanced, I don't think the TZ would work unless you have something extra hot and dark in the bridge. Even then, be prepared to have a very "unique"-sounding guitar that requires you to adjust your amp settings if you have it setup for more "normal"-sounding ones. If you're going for an intentional mismatch, and you're playing, I dunno, fuzzed out drone-y stuff or something where extra fat, dark, and hot is desirable, then yeah.
Take this for what it is, though. I have never tried a TZ in the neck. I have tried a JB, though, which has similar DCR and inductance, and I found that too dark, round, and kinda muddy, so I'm just assuming.
I think you can mod the hell out of the TZ, but maybe you can also run it in parallel or split for whenever you want some clarity. I bet split in the neck would sound nice.