I dont find the C5 to be finicky at all. Here is the spectrum I use it in:
Stratocaster
Ibanez RG570
Gibson Explorer
Sounds great in all!! I find this pickup shows the character of the guitar. For example, I used to use a tone zone and what ever I put it in, sounded similar. The C5 gives me the same feel/harmonics and such (feels familiar) in every guitar, but it lets the guitar's character come thru.