To me, even the hottest humbucker might do the job if wired in parallel.
But again, it depends on the sound wanted, not evoked until now.
That said, a testimonial: I've a 3 PUs guitar (initially HH) whose added mid pickup is a powerful silver foil single coil (mini-hum sized). As it has the inductance of a regular Gibson HB, I can obtain from it the same kind of tones than from a 3 PU's Les Paul in position 2.
I can also make the sound closer to the 2d position of a Strat by enabling a dummy coil / choke in parallel with the pickups.
The same kind of tonal tuning can be done by taking in account the specs of the pickups involved and applying a wiring adapted to these specs.
If two standard or underwound HB'shumbuckers are used in bridge and mid position, splitting each of 'em while they're in parallel should open to Fenderish tones (and maintain humbucking operation in two cases among 4 possibilities of split, if the wiring is properly designed).
If the bridge and mid slots host two powerful HB's, fitting each of them with a series/parallel switch should allow to go from fat greasy sounds to bright tones with various nuances in between (and humbucking operation in any case).
Again, it's a question of tonal desires and wirng design...