It's amazing how many tricks for dealing with conventional amps apply in digital models. Scream 808 or the legacy Screamer that has extra EQ into a 5150 and V30 4x12s with 0.0-1.0 gain, 5.0-7.0 tone, 8.0-10.0 volume is terrific for tight rhythm chug. New Pillars (Earthquaker Devices Plumes) is another fun TS-like, at least on some settings.
The Friedman HBE-100 model is just a killer modded Marshall sound.
If you want Led Zeppelin sounds, you should try a tele into a legacy Jumbo Fuzz (Tonebender), Soup Pro (Valco Supro S6616), and the 2x12 Match H30 or 1x12 Celest 12H. That's pretty much what Page used in the studio early on. Supro into a G12H30 is terrific. Can probably skip the Jumbo Fuzz if you are using a guitar with humbuckers.
Don't overlook the Revv (I like the Purple for rhythm, it's still got more than enough gain for crunch, and at lower gain is surprisingly dynamic, where the Red is awesome for saturated gain tones), Archetype Lead (PRS Archon), Line 6 Badonk, and PV Panama (Peavey 5150) all are different flavors of wonderful for metal. Cali IV Lead is tricky to dial in just like the real thing, Rectifier unfortunately lacks a lot of the switches that make the real recto unexpectedly flexible. And the Line 6 originals have a lot of surprises.
For Marshalls (aside from Friedman) I wound up generally preferring the Brit P75, it was easier to dial in for classic tones. Brit Trem is a bit closer to expectations than the Plexi. Derailed Ingrid is great at lower gain. I've been warming to the 2204, though.
And those are just highlights of my favorites of the styles you are messing around with, there's a number of other amps just in the high gain & Marshalloid variations, never mind all the Fendery, oddball antiques, and boutique models.
Have fun!
