Sure. When you see those traditional rows of Marshall stacks, often one is overdriven first and the others sorta carry the signal like slaves to the other cabs. & of course, some might be for backup or show, but ...
I have nothing against the Orange amps ive tried, but i hear an easy to get preamp distortion. So id settle for a Blackstar, or Seymour Duncan Mayhem pedal with a real preamp tube built in, & use that into a 6505, prob with the preamp low, the master hi.
But im a cheapskate, & havent heard the Dark terror yet.
So, to the OP, yes u could do that,...