Many years ago in those halcyon days of the early 80's, I did terrible things to a Strat with a chisel (okay, a screwdriver) and a hammer to make the ugliest swimming pool rout you've ever seen. It looked something like those terrible scenes from Illinois last month, major F4 damage in the heartland of that Strat.
Anyway, long story short, I ended up having a guy make a 27-inch scale neck for it, and I slapped a couple of humbuckers next to each each other, a Super D in the normal bridge position, and an Invader right next to it but with the near coil significantly unwound (still don't know how I did that without killing it). I wired it up so that the Super D was on one side of the switch and the other side of the switch was the partially de-wound near coil of the Invader in series with the Super D. It was about a 20k pickup, presumably all 43 AWG. So it was a steroid coil split, 2 in series or 3 in series. (The 4th coil, the other Invader coil, I used as a single coil middle pu.)
With the long 27" scale (and the necessary even thinner strings) it actually sounded pretty good but I think it would be mudsnake tone on a normal scale guitar.