Re: Why Not Use Instrument Cable?
This has been covered before many times, but I'll give you a quick explanation anyway.
The reason you use different kinds of cable is because you are dealing with two kinds of electric signal: high impedance (guitar to amp) and low impedance (amp to cab).
Your guitar sends a high impedance signal (very weak) to the amp. It is not susceptible to resistance on the cable (because it's already high impedance, a few extra ohms from the cable won't hurt it), but it is very vulnerable to RF interference. This is why guitar cables are shielded and use fairly thin wires.
The amp sends a low impedance signal to the speakers. This signal is not vulnerable to RF like a guitar signal because it is very powerful. It is, however, vulnerable to high impedance cables because the amp is only expecting a few ohms impedance, and any extra is going to change that. This is why speaker cable has no shielding and big conductors, like an AC power cord.
You can get away with using a speaker cable in place of a guitar cable, but you will probably notice you have more noise in your sound as a result. You can't get away with using a guitar cable for speaker cab connections because of the impedance problem explained above. At best you'll alter your tone, and at worst you'll wreck your output transformer.
Speaker cables are generally cheaper than guitar cables, so there's really no excuse for not using one.