Re: Will I notice new tube in my Mesa?
Mesa/boogie amplifiers are made with a fixed bias that cannot be adjusted without digging into the amp and modifying resistor values in the bias power supply. They don't re-bias when you put new tubes in. You put the new tubes in, and go. That's it. I agree that at 3-4 hours a week for 13 years the power tubes presently in there are long overdue for replacement. Contact Mesa, Groove Tubes, or the tube vendor of your choice and let them know you have a Boogie you want to re-tube. Any tube vendor worth their salt should be able to match up a set of tubes that will bias properly in your amp.
The phase inverter does drive the power tubes, but is still a normal preamp tube. It handles preamp levels of power, which are a couple orders of magnitude less than the level of power the power amp puts out, so there shouldn't be a reason why the phase inverter would need replacing alongside the power tubes, IMO.
Preamp tubes do last a long time. Hell, I've got some 1960s RCA tubes in my Nomad, and they're doing just fine. If none of the tubes are acting microphonic, then the preamp is fine and shouldn't need replacing. If you want to try some new preamp tubes in your amp to see what kind of tweaks you can make to the amp's tone, go right ahead.