Er, what precisely do you mean by two wire humbucker?
a) Single conductor + shield?
b) Two conductor + shield?
If the case of two con + shield, the wires of your HB could be hot and coiltap or either end of the HB as a whole. This will determine what trick wiring you can perform.
If your HB turns out to have a coiltap, it would be possible to immitate the Seymour Duncan personal Esquire wiring schematic BUT the sonic variations will not be quite the same. Your version would bring a large change in volume and RF hum.