So, I have an Epi Dot with a Seth Lover bridge and a '59 neck. I play through a Traynor YCV-40, which has a clean channel somewhat similar in character to a deluxe reverb.
The bridge is very bright/jangly, and the neck is a bit darker and more scooped with a gorgeous clean sound. It took me a while to get along with them - at first I'd EQ my amp to make the neck sound perfect and the bridge would be a little screetchy/bright. Then I'd EQ my amp to make the bridge sound perfect and the neck would be too boomy. I've got the Seth very close to the strings now, the '59 backed off a bit, and have adjusted the pole pieces on both to balance the strings. The '59 I angle the bass side a little further down than the treble side, the Seth I have flat.
I love 'em now. The neck is clear and refined. Works great for jazz with the tone and volume rolled a little bit off. Works great for blues and rock solos with the tone and volume all the way up. The bridge is bright and jangly, but not overbearing. It cuts through pretty well and sounds decent for classic rock and even some hard rock stuff. I usually keep the volume up all the way and the tone rolled slightly off. There's a lovely singing tone that it gets if you roll the tone further back. If you get it up to metal levels of gain at any volume you'll be dealing with a lot of feedback, although this is controllable with some careful string muting and angling of the guitar.
Volume wise, they balance pretty well as I've got them now, but the '59 has more output than the Seth, so you have to keep it further from the strings. If I had to pick only one, I really like the '59 neck tone. You can EQ it so that it takes on an almost acoustic quality clean, and it's lovely and round for edge of breakup leads.
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