Depends on your physiology - literally how strong your fretting hand/arm is. Classic rock and blues requires bending (LOTS of bending) so your hand has to be able to do that with accuracy (which includes knowing when to overbend). For all my electric guitars, I have 11-49 D'Addario or Ernie Ball as standard - and I have for nearly 30 years, so I'm used to them. Put me on a guitar with 9s or even 10s and I have to work hard to calm myself down - even fretting and keeping tune is tough because of finger pressure issues - I can do it, just have to work at it. I would try an extended period at each gauge (3 months or more) to see how you settle with each gauge.
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