I think the more guitars you've sunk into over time, the less it matters. There may be some profiles that I don't like, but then, I wouldn't own them. ie, overly fat or skinny.
My hands are mostly used to Fender Am Std, Gibson 50's, and PRS wide/fat. I didn't used to like slim 60's, but I'm growing to like it.
So my answer is. I don't care. It doesn't matter. I like all my guitars. There is no best.