I would say it's more of a space issue than weight issue. Unless you are the only one in the band, which wouldn't be much of a band with just one person, there will always be more than yourself moving it. Two people can easily carry a 412. Looking at the Avatar site, the 212s have the same width and depth of a 412, and the 412 is only 9-10 inches taller. Unless you have limited space to move or store or have limited stage space... I personally would go 412. If space is limited a good quality 212 should have the same tonality of a 412. Either way, it will be good
I'm just a sucka for the 412 mojo myself... it's a curse...
I guess that wasn't much help... but something to think on. Two 212's will take more space than one 412.
Nathan